Link: NCBI PubMed
Summary
Ontologies are becoming increasingly important in bioinformatics because they can be linked to the information in databases and their knowledge then used to query the databases. This direct connection allows for faster searching in databases and less ambiguity than in string-based searches. Also, lots of data contains hierarchical relationships and relational databases do not handle hierarchies very well. The result is rich ontologies, which are independent of their associated databases and linked to them through term IDs.The Gene Ontology (GO) is used to integrate genetic data about gene products with our knowledge of their properties. The GO catalogues its knowledge in three essentially non-overlapping ways: their location within cells, the process to which they contribute, and the functions they fulfill.
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